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Whether the person being diagnosed is you or a loved one, the term breast cancer can be terrifying to hear. Learning more about the type of breast cancer you have can help you make better decisions about the therapies you use to win the fight against it. Considering medical marijuana card online as a treatment is one of the several possible therapies you can use. Marijuana has been proven to help individuals find relief from the side effects of cancer treatments, but it might also help treat the cancer itself. What is ER PR Breast Cancer? Breast cancer comes in several types, which differ in their aggressiveness, growth patterns, and receptor status. When an initial diagnosis of breast cancer is made, additional testing will be conducted to determine the type and stage of the cancer. During this testing, hormone receptors will be identified. ER and PR types of breast cancers are labeled depending on the receptors found in the cancer cells. ER refers to estrogen receptors and causes ER positive or negative breast cancer. PR refers to progesterone receptors and can be either PR positive or PR negative breast cancer. It is possible for both ER and PR to be positive or both to be negative. There can also be variations like ER positive PR negative breast cancer. The cancer’s ER/PR Status  can make a difference in the treatments and therapies used. Breast cancers that test positive for estrogen receptors or with breast cancer PR positive, hormone therapy and hormone-blocking treatments may be useful in treating cancer. When estrogen or progesterone receptors are not present, hormone therapy is not effective. ER PR positive breast cancer treatment will include hormone therapy along with typical treatments like surgical intervention and chemotherapy. Hormone therapy can provide an edge in these cases, which is why breast cancers that are negative for hormone receptors like these are especially aggressive and difficult to treat. Patients who suffer from non-ER or PR breast cancer may be the most difficult to treat. How Marijuana Affects Cancer and Cancer Side Effects Marijuana has been used as a medical treatment throughout history, being used to treat physical, mental, and emotional illness with well-documented success. Recently its benefits as a treatment  for various types of cancer and cancer-related side effects has been explored. Some patients and medical professionals have shown very promising results when adding cannabis to their cancer treatment plans. This is because cannabis contains compounds like THC and CBD that have been shown  to help reduce tumor growth, inhibit the growth of cancerous cells, and reduce the spread or metastasis of cancer throughout the body. This is because the chemical compounds in marijuana, also called cannabinoids, work within the body to improve the function of certain systems like the neurological and immune system. Marijuana and its related compounds have also been shown to help with the side effects associated with many common cancer treatments. It can help with the nausea and lack of appetite associated with chemotherapy and radiation treatments. It has also been shown to reduce pain and inflammation as well, which can help reduce discomfort associated with cancer and related therapies. Its pain-relieving capacity can help patients coping with painful tumors and post-surgical pain during recovery. Cannabis has also been linked to improving mood and reducing stress, which could make it easier to cope with the emotional effects of cancers like breast cancer. How Cannabis Interacts with Receptors in Breast Cancer To be useful in treating breast cancer, cannabis must improve its symptoms, destroy or inhibit the growth of cancer cells, or both. There is hope that marijuana can aid in both ways to truly relieve breast cancer. This is because cannabis may be able to interact with receptors in breast cancer. According to Cancer.gov , research shows that cannabinoids can activate receptors in various parts of the body. This means it could be useful in triggering or turning off certain bodily functions, like the production of cancerous cells. Reported research on their site also shows that cannabis has been proven effective in symptom relief, including being recognized for relieving side effects like nausea, vomiting, and pain. Cannabis is not only effective at treating symptoms and complaints associated with breast cancer. Medical marijuana card online may also be able to aid in the treatment of specific types of breast cancer, including ER PR breast cancer and ER PR negative breast cancer. How Marijuana Can Relieve ER PR Breast Cancer Marijuana may help treatbreast cancer. Both THC and CBD have been shown to inhibit tumor growth  and aid in restoring the natural cycle of cell death. This was true in cases of breast cancer with estrogen positive markers. In fact, marijuana makes an effective ER PR positive breast cancer treatment because the same studies have shown it has helped kill off estrogen receptor positive cell lines. This means that marijuana compounds can also help relieve ER positive PR negative breast cancer because cannabinoids can target estrogen receptors that are found in breast cancer cells. How Marijuana Can Relieve ER PR Negative Breast Cancer Cannabinoids are also effective when used to treat ER negative and PR negative breast cancer. The presence of estrogen receptor cells in breast cancer is not necessary for cannabis to reduce tumor growth. THC and CBD are capable of killing estrogen negative cells too. Cannabinoids can trigger cell death, reduce the amount of nutrients the tumor is capable of diverting from normal cells, and reduce the likelihood that breast cancer cells will spread by targeting non-estrogen receptors. The compounds in cannabis may effectively treat any type of breast cancer whether it is receptor positive or negative. How to Treat Breast Cancer with Marijuana When used as a treatment for cancers and side effects, marijuana can be inhaled or ingested. Current research indicates that inhalation is still one of the most effective ways to get the compounds into the bloodstream quickly. Pharmaceutical research has focused on isolating cannabinoid compounds and producing them synthetically. Currently, synthetic CBD and THC have been developed and are being tested in pill, liquid, and oral spray formats. At least three prescription drugs on the market in the U.S. today are made with medical marijuana card online compounds according to USA Roday . In states where medicinal or recreational marijuana has been legalized, the production of highly concentrated cannabis oils is also being conducted, and that oil is becoming a common therapy method. As both receptor positive and receptor negative breast cancers have been shown to respond to treatments with medicinal marijuana, more and more research has been conducted to determine if it can be used to treat breast cancer. Some users have found treatment with a concentrated oil made of high-grade cannabis is an effective treatment when used post-surgery or in addition to treatments like chemotherapy. Proponents believe the only reason that cancer would not respond to cannabinoid treatments is that a high enough grade or dose was not being used. This oil version of ingested therapy is the most popular, but additional research must be done to determine which delivery method is most effective for treating breast cancer. Why People with Breast Cancer are Choosing Cannabis as a Treatment People are choosing marijuana as a medical treatment with increasing frequency as it becomes more acceptable. Although popularity may have something to do with why more individuals with breast cancer are trying cannabis, there are numerous benefits that make it a growing choice for breast cancer patients. The primary motivator behind many who choose to add cannabis to their treatment plan is its ability to reduce common side effects of other treatments. Marijuana can help improve mood, reduce stress, combat pain from tumor growth and surgery, improve appetite, and reduce nausea and vomiting associated with treatments like chemotherapy. This makes treatments easier to manage, allowing doctors to more aggressively attack the cancer. The other reason so many breast cancer sufferers are trying cannabis as a treatment its recently documented ability to inhibit cancer cells. Even agressive breast cancers  have shown improvement when treated with marijuana. It can reduce cell growth, prevent tumors from diverting nutrients from healthy tissues, inhibit the spread of cancer, and trigger the death of cancerous cells. All while leaving surrounding healthy tissues unaffected. This is where cannabis treatments really differ from other common cancer therapies, which typically do harm to healthy tissues or disrupt other bodily systems. Marijuana attacks cancer cells while promoting overall health. This is why it is becoming a preferred treatment for breast cancer patients. Although a breast cancer diagnosis can be devastating, advances in our knowledge and use of medicinal marijuana leaves some hope. Breast cancer may have estrogen and progesterone receptors or it may not. Determining if a patient has ER or PR breast cancer has been an important first step in developing a cancer treatment plan. Adding cannabis to your cancer treatment plan can provide some benefit regardless of if your cancer is ER/PR negative or if the breast cancer PR positive. Inhaling or ingesting medical marijuana card online у as a cancer treatment can help with side effects or aid in reducing tumor size and spread. Because of its proven effectiveness, marijuana is being used by more and more breast cancer patients. References 1. Web-site breastcanser.gov An article “Hormone Status” URL: http://www.breastcancer.org/symptoms/diagnosis/hormone_status 2. Web-site cancer.gov An article “Cannabis PDQ” URL: https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq 3. Web-site cancer.gov An article “Cannabis PDQ” Section 7. URL: https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq#section/_7 4. Web-site Live Saving Natural Cures and Natural Remedies An article “Cannabis oil as a breast cancer treatment estrogen positive.” URL: http://www.life-saving-naturalcures-and-naturalremedies.com/cannabis-oil-as-a-breast-cancer-treatment-estrogen-positive.html 5. Web-site medicaljane.com An article “Cannabis may treat agressive forms of breat cancer” URL: https://www.medicaljane.com/2013/10/17/study-cannabis-may-treat-aggressive-forms-of-breast-cancer 6. Web-site usatoday.com An article “Three drugs that come from marijuana” URL: http://www.usatoday.com/story/money/personalfinance/2014/03/17/three-drugs-that-come-from-marijuana/6531291/
Medical Marijuana in Pediatric Medicine Posted by Mark Sircus - Director on 19 August 2010 | Filed under Medicine "Cannabis can realize its full therapeutic potential only when it is completely legal and people donâ€™t have to go to their doctors to get it." Dr. Grinspoon Many physicians, even in California, refrain from approving use of cannabis by patients out of residual fear. Countless others refrain because they learned nothing about cannabis in medical school and cannot knowledgeably advise patients about dosage, side effects, or mechanism of action. This is of course not an acceptable situation, especially in pediatric care, because it is so useful and safe and potentially lifesaving in certain cases. The stigma associated with â€œmarijuanaâ€ presents powerful discouragement to doctors. Inhumane federal laws, which list marijuana on Schedule 1 of the Controlled Substances Act, the tier reserved for drugs with â€œno currently accepted medical use,â€ continue to keep marijuana away from doctors even though everyone knows this is as far away from the truth as anyone can go. The United States government enjoys its cruelty as has been demonstrated by its â€œwar against drugs.â€ Cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals and also kill cancer cells. Their use in the case of childhood cancer is compassionate. Marijuana is brimming with healing compounds and doctors 100 years ago understood this simple fact; that was the reason pharmacies always made it available to the public. Iodine and marijuana were principle medicines used in the 19th and very early part of the 20th century. Both were forced from the consciousness of modern physicians who became mentally enslaved to pharmaceutical interests that got doctors more interested in money and poisoning than in helping patients with safe and effective medicines. Cannabinoids are usually well tolerated, and do not produce the generalized toxic effects of conventional chemotherapies. Marijuana is an extremely broad acting and universally useful medicine with appropriate application for most disease conditions. Crohnâ€™s disease patients credit the plant with helping reverse their debilitating intestinal disorders, and accredited research suggests its use in dealing with and preventing diabetes, heart disease, Alzheimerâ€™s and assorted maladies arising from chronic inflammation. Tetrahydrocannabinol (THC) and natural cannabinoids counteract cancer and chemical toxicity from drugs and environmental sources thus helping to preserve normal cells. Not many people or physicians realize how useful or even critical medical marijuana can be in pediatrics â€“ or how it can save many childrenâ€™s lives. We are talking about serious medicine and the pharmaceutical companies know this and are making synthetic versions of THC, but synthetic copies cannot compete with the real thing in terms of safety and effectiveness. Knocking on deathâ€™s door, 10-year-old Joey Perez was slowly dying. The potpourri of prescription medications heâ€™d consumed since the age of five had damaged his body beyond repair â€“ the side effects were literally killing him. Joey was diagnosed with autism at 18 months old. At one point, he was taking six different medications â€“ up to three times a day. As a result of the side effects, Joey became malnourished and was diagnosed with anorexia. Every day, his condition got worse. His eyes were sunken in and you could easily see all the bones in his chest. He was refusing to eat. At the end of his allopathic treatments his medical prognosis was high probability of death within six months. Today Joey is thriving and his mother has been on The Good Morning Show to share that the Compassionate Use of Medical Marijuana saved her sonâ€™s life. â€œAlthough medical marijuana is not known to be a cure for autism, it has been proven to facilitate â€˜lifeâ€™ for my son and has ushered him into his most progressive developmental period ever. 12 Months After Marijuana Treatments Today at age 11, Joey is flourishing with new communicative expressions, heâ€™s gained over 40 lbs, and heâ€™s happier, healthier, better behaved and is more productively active than ever before. Before we began to give him treatments of oral marijuana he was a danger to himself and others. He had suffered from anxiety, OCD, and aggression since an early age. At the age of five, Joey was prescribed the first of many ineffective, harmful medications. The medications he was prescribed at that time worked for about a year but Joey refused to eat and that was the beginning of their story. As a result of the serious side effects, Joey became malnourished and was diagnosed with anorexia. It was the famous marijuana brownies that saved my sonâ€™s life and it was the doctors and their pharmaceutical medicines that almost killed him. â€œIt seems to me if one is going to need to use drugs, one ought to consider a relatively safe drug, like marijuana,â€ said Bernard Rimland, Ph.D. of the Autism Research Institute. Marijuana, the forbidden medicine, seems to be useful for some people with adult attention deficit disorder, impulse disorders and bipolar disorder. Some families have found marijuana to be nothing short of miraculous. Some of the symptoms marijuana has ameliorated include anxiety â€“ even severe anxiety â€“ aggression, panic disorder, generalized rage, tantrums, property destruction and self-injurious behavior. One mother commenting on using marijuana for her autistic child said, â€œI know itâ€™s not the end all answer but itâ€™s been the best answer for the longest time for us in regards to ALL the other medications. I cannot tell you how many months we would go on a medication wondering if it was doing anything, anything at all. Here we can see the difference in 30-60 minutes guaranteed.â€ Patients report medical marijuana as more therapeutic and better tolerated than other medications. Dr. Rimland continues saying, â€œClearly, medical marijuana is not a drug to be administered lightly. But compare its side effects to the known effects of Risperdal, which include massive weight gain, a dramatically increased risk of diabetes, and an elevated risk of deadly heart problems, as well as a host of other major and minor problems. Other psychotropic drugs are no safer, causing symptoms ranging from debilitating tardive dyskinesia to life-threatening malignant hyperthermia or sudden cardiac arrest. Of all drugs, the psychotropic drugs are among the least useful and most dangerous, and the benefit vs. risk profile of medical marijuana seems fairly benign in comparison.â€ He continues, â€œThe reports we are seeing from parents indicate that medical marijuana often works when no other treatments, drug or non-drug, have helped.â€ Recently, researcher Dr. Ester Fride of the Behavioral Sciences Department of Israelâ€™s College of Judea and Samaria published a pair of scientific papers stating that the brainâ€™s cannabinoid receptors (receptors in the brain that respond pharmacologically to various compounds in cannabis as well as other endogenous compounds) and the naturally occurring messenger molecules that activate and bind to them (so-called endocannabinoids) â€œare present from the early stages of gestationâ€ and may play â€œa number of vital rolesâ€ in human prenatal and postnatal development. Writing in Neuroendocrinology Letters and the European Journal of Pharmacology, Fride suggests, â€œA role for the endocannabinoid system for the human infant is likely.â€ She notes that in animals, the endogenous cannabinoid system fulfills several important developmental functions, including: embryonal implantation (which requires a temporary and localized reduction in the production of the endocannabinoid anandamide), neural development, neuroprotection, the development of memory and oral-motor skills, and the initiation of suckling in newborns. A dysfunctional endocannabinoid system, Fride speculates, may be responsible for certain abnormalities in infants, particularly â€œfailure-to-thriveâ€ syndrome, a condition in which newborns fail to properly grow and gain weight. (In animal studies, mice fail to gain weight and die within the first week of life when their cannabinoid receptors are blocked.) Dr. Fride strongly recommends the use of cannabinoids in pediatric medicine. She notes that â€œexcellent clinical resultsâ€ have been reported in pediatric oncology and in case studies of children with severe neurological diseases or brain trauma, and suggests that cannabis-derived medicines could also play a role in the treatment of other childhood syndromes, including the pain and gastrointestinal inflammation associated with cystic fibrosis. Research presented at the International Conference for Autism Research in Montreal in June of 2006 of 275 children found serious intestinal inflammation in autistic children identical to that described by Dr. Andrew Wakefield. Gut biopsy tissue from 82 of these children reveals that 85% have evidence of the measles virus in their inflamed intestines. The news is a huge embarrassment for the Department of Health in England, which has unjustly crucified Dr. Wakefieldâ€™s research. Marijuana cuts lung cancer tumor growth in half, a 2007 Harvard Medical School study shows. The active ingredient in marijuana cuts tumor growth in common lung cancer in half and significantly reduces the ability of the cancer to spread. Because the development of the cannabinoid receptor system appears to occur gradually over the course of childhood, â€œchildren may be less prone to the psychoactive side effects of THC or endocannabinoids than adults,â€ Fride writes. â€œTherefore, it is suggested that children may respond positively to the medicinal applications of cannabinoids without [psychoactive] effects.â€ She concludes, â€œThe medical implications of these novel developments are far reaching and suggest a promising future for cannabinoids in pediatric medicineâ€ for conditions including cachexia (severe weight loss), cystic fibrosis, failure-to-thrive, anorexia, inflammation, and chronic pain. â€œItâ€™s clear that the cannabinoid system is essential for complete human development, and that cannabis medicines have a great potential to help sick children,â€ says University of Southern California professor Mitch Earlywine, author of the book, Understanding Marijuana: A New Look at the Scientific Evidence. â€œGiven the well-established safety of the medication, clinical trials for other disorders, particularly cystic fibrosis and â€˜failure-to-thrive,â€™ seem a humane and essential next step.â€ Nausea appetite loss, pain and anxiety are all afflictions of wasting, and all can be mitigated by marijuana. Institute of Medicine In test-tube experiments, researchers at the National Institutes of Health (NIH) in Bethesda, Md. exposed rat nerve cells to a toxin that is typically released during strokes. Cannabidiol reduces the extent of damage researchers reported to the National Academy of Sciences. More effective than vitamins C or E, strong antioxidants such as cannabidiol will neutralize free radicals and so might limit the damage and reduce the severity of ischemic strokes. â€œMarijuana has remarkably low toxicity and lethal doses in humans have not been described. This is in stark contrast to a number of commonly prescribed medications used for similar purposes, including opiates, anti-emetics, anti-depressants, and muscle relaxants, not to mention legal substances used recreationally including tobacco and alcohol,â€ writes Dr. Gregory T. Carter, Clinical Associate Professor of Rehabilitation Medicine, University of Washington School of Medicine. Pharmaceutical companies are for drugging preschoolers with Ritalin even though about 40% of children developed side effects and roughly 11% dropped out because of problems including irritability, weight loss, insomnia and slowed growth. â€œPreschoolers on methylphenidate, or generic Ritalin, grew about half an inch less and gained about two pounds less than expected during the 70-week study. This is a catastrophe. It just opens up the way for drugging the younger kids,â€ said Dr. Peter Breggin, a New York psychiatrist and longtime critic of psychiatric drug use in children. Breggin said the research is part of a marketing push by the drug industry to expand drug use to the youngest children. â€œI found babies, 2-year-olds, 3-year-olds being given mind-altering drugs,â€ says Carole Keeton Strayhorn, Texasâ€™ state comptroller. Strayhorn conducted a two-year investigation into allegations that foster kids in Texas are over medicated. â€œChildren in foster care in Texas are dying. Children in foster care are being drugged,â€ Strayhorn says. If we concede that child psychiatrists are not absolutely out of their minds themselves, we can grant that there is a real need for something to calm down these children but certainly to poison them with a very toxic medicine when their brains are still forming is outside the range of medical reason. It is an insane paradigm and a cruel system of government that would keep the safest and most effective drug out of the hands of parents and the most harmful toxic medicines legal â€“ medicines that are addictive and can ruin a childâ€™s entire life. The American College of Physicians (ACP) has urged the government to reverse its ban on medical treatments using marijuana. â€œACP encourages the use of non-smoked forms of THC (the main psychoactive element in marijuana) that have proven therapeutic value.â€ The Philadelphia-based organization, the second largest doctors group in the United States, cited studies into marijuanaâ€™s medical applications such as treating severe weight loss associated with illnesses such as AIDS, and treating nausea and vomiting associated with chemotherapy for cancer patients. Richard Cowan said, â€œThe suppression of medical cannabis is mass murder, but in the real world it is simply cannabis prohibition itself that assures that tens of millions of people will die sooner and with far greater suffering than would be the case if they had easy access to this plant. Even Saddam Hussein has not caused so much pain and suffering. Cannabis prohibition is indeed a weapon of mass destruction that no government wants to acknowledge.â€ The easiest way for doctors to learn about the pharmaceutical dynamics of marijuana is to self-prescribe it for themselves. Firsthand experience is valuable and not dangerous since it is nontoxic, even at high dosages. Marijuana certainly is a mind opener, thus we can understand why the federal government is against it. But in pediatric medicine we have to open our hearts and minds to everything that will help our young charges. This does not come easily to pediatricians who are following the lockstep of the government with their obsession with dangerous vaccines, meaning most pediatricians would have a mental and emotional breakdown if they were to acknowledge the harm they are doing. It is very difficult to use marijuana and maintain oneâ€™s rigid mental positions; though not quite a truth serum, itâ€™s close. Again this is another reason the federal government is so much against its mind-moderating ways.  Amtmann D, Weydt P, Johnson KL, Jensen MP, Carter GT. Survey of cannabis use in patients with amyotrophic lateral sclerosis. Am J Hosp Palliat Care. 2004;21:95-104.  www.primidi.com/2004/09/05.html  Joy JE, Watson SJ, Benson JA. Marijuana and Medicine: Assessing the Science Base. Institute of Medicine. Washington, DC: National Academy Press; 1999.  Science News, Vol. 154, No. 2, July 11, 1998, p. 20.  www.redorbit.com/news/health/1259095/doctor_group_endorses_medical_marijuana/ http://blog.imva.inf...iatric-medicine