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My husband has been using 2 doses rectally .5 with oral syringe for the last 24 days. He is also having chemo treatments 1 every 3 weeks, so far he has had 2. The 3rd chemo will be 4/5 and a pet scan 4/26. I know from a friend who's Husband was staged 4 with lung, brain, liver and numerous tumors in his abdomen that it gets worse before it gets better. Today he had to take a pain pill. for a tight feeling/ pain a little different then what he use to have. Could the tumor be shrinking causing pain or growing. I prefer to believe it's shrinking but has anyone had experience with this kind of cancer? At the junction of the esophagus and stomach.